Vcheck SDMA Demonstrates Exceptional Accuracy in Peer-Reviewed Study

   Bionote announced that the outstanding performance of its Vcheck SDMA has been validated in a recent study published in the SCI-indexed American Journal of Veterinary Research.   The study revealed that Vcheck SDMA showed a strong correlation (r = 0.93) with laboratory-based reference SDMA results and outperformed other point-of-care (POC) analyzers in consistency and reliability. These findings highlight the test’s robustness and practical utility for in-clinic use.   Importantly, when Vcheck SDMA results were applied to IRIS guidelines for chronic kidney disease (CKD) staging, the test achieved a 93% agreement with reference laboratory staging—the highest among all POC SDMA analyzers evaluated in the study.   To access the full article, click [here], or click [here] to view a summary of the findings.   The Vcheck SDMA 2.0 kit, launched in Q2 of 2025, continues to offer a streamlined testing workflow with trusted analytical performance.   For product information or availability, please contact your regional manager. 

• 2025.08.19
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BIONOTE Launches Vcheck SDMA 2.0 — Simpler Renal Testing with Trusted Performance

  BIONOTE announced the launch of Vcheck SDMA 2.0, an upgraded diagnostic kit for early detection of kidney disease in dogs and cats. SDMA (symmetric dimethylarginine) is a reliable biomarker that reflects glomerular filtration rate (GFR), enabling earlier diagnosis of renal dysfunction than traditional markers.The new SDMA 2.0 kit offers a simplified testing process while maintaining the accuracy and performance of the original version. It is designed for routine screening, monitoring of AKI and CKD, and evaluating kidney function in senior or critically ill patients.A BIONOTE spokesperson stated, “Vcheck SDMA 2.0 enhances convenience at the clinic without compromising reliability. It strengthens our commitment to providing practical and precise diagnostic tools for veterinarians.”View product details

• 2025.06.19
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Bionote's Vcheck T4 Diagnostic Kit Proven Effective in International Journal

Bionote's Vcheck T4 kit was recently validated for its outstanding performance, with results published in the Journal of Feline Medicine and Surgery, a leading international journal in feline clinical research, this past January.  The study, titled "Evaluation of a point-of-care test for quantitative determination of total thyroxine in feline serum," was conducted to verify the performance of the Vcheck T4 assay for feline thyroid function testing.  Hyperthyroidism is a common endocrine disorder in adult and senior cats. Early detection and treatment are crucial, yet diagnosis is often delayed due to its nonspecific clinical signs. In such cases, total thyroxine (TT4) evaluation serves as the most widely used primary diagnostic tool.  In this study, the Vcheck T4 demonstrated excellent reproducibility with a coefficient of variation (CV) ranging from 3.7% to 11.0%, showing performance comparable to the reference enzyme immunoassay (EIA) method.  Furthermore, as a diagnostic tool for feline hyperthyroidism, the Vcheck T4 assay showed a sensitivity of 88.9% and a specificity of 84.4%, indicating its clinical utility in evaluating thyroid function in cats.  The research team stated, "The Vcheck T4 assay provides precise and reproducible TT4 concentration results," adding that it is "a valuable tool for routine screening and ruling out hyperthyroidism in adult and senior cats."Click here for the full paper

• 2025.02.21
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