The Korea International Trade Association announced that BIONOTE won the prize of ‘$100- Million Export Tower’ in exports at the 58th Trade Day ceremony. The Ministry of Trade and the Korea International Trade Association hold a ceremony every December 5th to mark Trade Day, and select and reward companies that have contributed to export performance, such as pioneering overseas markets and creating jobs. BIONOTE is a company specializing in diagnostic devices for animals with 19 years of business experience and has branches in the U.S. and Shanghai, China, where the diagnostic market is large. BIONOTE obtained United States Department of Agriculture (USDA) approval for the first time in Korea and succeeded in entering overseas markets in recognition of the accuracy of various products such as the world's first development of Middle East Respiratory Syndrome (MERS) simple diagnostic kits and World Organization for Animal Health (OIE) certification. Based on its core source technology, the company has a portfolio of various products such as rapid diagnosis (Rapid), fluorescent immunoassay (Immunoassay), and enzyme Immunoassay (ELISA) for disease diagnosis. In particular, Vcheck which is the main diagnostic device of the bio-note is receiving high response at home and abroad as it can quantitatively measure various biomarkers based on fluorophores with excellent sensitivity, and recorded 110% year-on-year sales growth. Next year, serum chemical analysis equipment with high market demand and Point of Care (POC) molecular diagnostic equipment capable of quantitative polymerase chain reaction (PCR) testing at the site will be released to expect greater sales growth.
A paper on the analytical validation of Vcheck cCortisol has been published in the international journal, Medycyna Weterynaryjna (Science Citation Index Expanded). See the attached file for the full paper. (Paper: Medycyna Weterynaryjna 77(08):6562-2021) In dogs, serum cortisol concentration can be useful for the diagnosis of adrenal and pituitary disorders. Interpretation of serum cortisol concentration is crucial in the diagnosis and management of dogs with both hyperadrenocorticism and hypoadrenocorticism. In this study conducted at University of Life Sciences in Lublin, Poland, non-fasting blood samples were obtained from 44 dogs. Cortisol results obtained by the Vcheck analyzer were compared to those obtained by the IMMULITE 2000 immunoassay, which had previously been validated for the measurement of serum cortisol concentration in dogs. As a result, Pearson’s Correlation analysis shows a very high consistency of the results obtained by the two analyzers (r=0.94, Fig. 1). The Bland-Altman test of agreement demonstrated that the Vcheck produced results close to those obtained by the reference method (Fig. 2). According to this study, the results of the Vcheck method were comparable to those of the IMMULITE 2000 reference method, which makes it suitable for canine serum cortisol analysis for the diagnosis of adrenal disease. Vcheck cCortisol can be quantitatively measured using a fluorescent immunoassay analyzer, Vcheck, in a short time (20 minutes) and can be tested using a small amount of sample (serum 50 µl). It also has a wide measurement range of 1 to 30 µl/dl.
Bionote, a leading veterinary diagnostic company based in Korea, is introducing a new biomarker, TnI, as a part of the Vcheck series. Vcheck Canine TnI is an in vitro diagnostic test kit for the quantitative measurement of cardiac Troponin I (TnI) concentration in canine serum. This test kit precisely quantifies the degree of elevation in TnI levels in dogs. Troponin consists of 3 subunits (troponin I, T, and C) which together function as the molecular switch of cardiomyocyte contraction. Among them, cardiac Troponin I (TnI) is a sensitive and specific circulating marker of cardiac injury for dogs. Cardiac injury causes the release of TnI into the circulation, where its concentration is correlated to the severity of the damage. Vcheck Canine TnI can provide important diagnostic and prognostic information in patients with cardiovascular or non-cardiac diseases as a cardiac injury marker of choice. A combined measurement of TnI and NT-proBNP is prognostically superior to measuring each alone in dogs with mitral valve disease (MMVD). NT-proBNP is also one of the Vcheck biomarkers. Vcheck Canine TnI: This one-step test procedure is easy to follow and provides fast results within 10 minutes using serum samples from dogs. Meanwhile, Vcheck Feline TnI, which measures cardiac TnI in feline blood, will be released later this year. If you are interested in Vcheck Canine TnI, please contact your local distributor or mail to [bionote@bionote.co.kr].