Bionote's Vcheck T4 kit was recently validated for its outstanding performance, with results published in the Journal of Feline Medicine and Surgery, a leading international journal in feline clinical research, this past January.

The study, titled "Evaluation of a point-of-care test for quantitative determination of total thyroxine in feline serum," was conducted to verify the performance of the Vcheck T4 assay for feline thyroid function testing.

Hyperthyroidism is a common endocrine disorder in adult and senior cats. Early detection and treatment are crucial, yet diagnosis is often delayed due to its nonspecific clinical signs. In such cases, total thyroxine (TT4) evaluation serves as the most widely used primary diagnostic tool.

In this study, the Vcheck T4 demonstrated excellent reproducibility with a coefficient of variation (CV) ranging from 3.7% to 11.0%, showing performance comparable to the reference enzyme immunoassay (EIA) method.

Furthermore, as a diagnostic tool for feline hyperthyroidism, the Vcheck T4 assay showed a sensitivity of 88.9% and a specificity of 84.4%, indicating its clinical utility in evaluating thyroid function in cats.

The research team stated, "The Vcheck T4 assay provides precise and reproducible TT4 concentration results," adding that it is "a valuable tool for routine screening and ruling out hyperthyroidism in adult and senior cats."

Click here for the full paper