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QCan whole blood, serum or plasma be specimen for detection?A
Theoretically, it is possible to use them during viremic period.
But blood sample is very limited to applicate because viremic period is relatively short compared to canine parvovirus pathophysiology.
So sample for FPV Ag kit should be feces. Also, in our instruction for use, blood or serum sample is not included.
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QHow about vaccine effect of FPV Ag kit detection?A
Unlike canine parvovirus vaccine of dog, feline panleukopenia virus vaccine can affect rapid FPV kit, According to article, there are different virus shedding competence for different commercial vaccine, and detect ability was also different for each commercial kit. It seems like vaccine interference period is about 1 week of post vaccination. So care should be done for result interpretation for FPV diagnosis for cat which vaccinated recently
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QIs canine parvovirus infection possible in cat? And is it also possible that Bionote rapid kit can detect it?A
Canine parvovirus can infect cat. Clinical signs of CPV infection in cat are almost same with FPV infection but severity is different.
Generally, CPV infection in cat is mild and chance of survival is higher than FPV infection. Since the two viruses has high genetic homology, Bionote FPV Ag kit can also detect CPV infection in cat, but Practitioner should aware that CPV infection in cat has very limited virus shedding period (2~5 days), Care should be taken for test result interpretation.
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QHow about virus shedding period of feline panleukopenia virus for rapid kit use?A
Virus shedding period of feline panleukopenia infection is relatively short.
Unlike parvovirus infection in canine which has 1 month of shedding period, feline panleukopenia virus shedding occurs approximately 2~10 days of exposure.
Understanding this difference is important for diagnosis of FPV.
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QCauses of False Positive for FPV Ag test kitA
1. In terms of utero infection, the affected litter can be clinically healthy probably due to their innate resistance or the acquisition of maternally derived antibodies(MDAs).
Still, these kittens can harbor the virus for up to 2 months after birth. (Csiza et al., 1971a)
2. Not all cats infected with FPV develop clinical signs and the severity depends on age, immune status, and concurrent infections (Foley et al., 1999)
3. Cats can test positive for up to 3 weeks after modified live vaccination (Neuerer et al., 2008)
4. The greatest fecal virus shedding corresponds with the peak of clinical disease, but keep in mind that the virus can be shed for up to six weeks after recovery7 and
that subclinical animals can also shed virus. (Greene et al., 1998)