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Our FIV Ab test detects IgG antibodies against FIV.

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Rapid Ab test may show negative results in very initial or terminal phase. It is known that in case of FIV, the antibody begin to develop after 60 days of exposure in most cats, and development of detectable antibodies may be considerably delayed in some cats. In terminal cases, compromised immune system result in lack of antibody development which may show negative results regardless of severe clinical signs. The latter fits in this case. We recommend you to repeat test minimum of 60 days after the last potential exposure.

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FIV vaccination induces humoral immunity, leading to the development of antibodies, and standard antibody tests cannot differentiate between vaccination and natural infection. In young cats receiving their initial vaccination, the vaccine history or another DIVA method should be checked to avoid misdiagnosis. There are numerous cases where uninfected cats are misdiagnosed with infection, which can result in inappropriate lifestyle changes or even euthanasia. 

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Cats infected with FIV have low levels of viral antigen in their blood, which has prevented the use of inclinic screening assays based on antigen detection as used in diagnosis of feline leukemia virus (FeLV). However, cats with FIV generally produce high levels of antiviral antibodies. Since FIV produces a persistent, lifelong infection, detection of antibodies in peripheral blood of unvaccinated cats is considered sufficient for routine diagnostic screening.

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The Bionote Rapid FIV Ab Test Kit has a high probability of differentiating between field infection and vaccination. However, in young cats that have received their initial FIV vaccination within the last six months, there is a possibility of interference.